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8 Hydrating Serums with Glycerin and Hyaluronic Acid for Dry Skin

Find your match for deeper, longer-lasting hydration—whether you layer under moisturizer or wear alone.

Curated by the 8Similar Editorial Team · AI-assisted

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Quick Look Overview

Dry skin doesn't just feel tight—it can exaggerate fine lines, compromise your barrier, and make makeup settle unevenly. As hydration science has advanced, serums combining glycerin and hyaluronic acid have become a foundational step for drawing moisture into the skin and keeping it there, offering a lightweight alternative to heavy creams that can clog pores or feel greasy under sunscreen.

How we choose

This roundup highlights seven serums and one gel-cream hydrator that use glycerin alongside hyaluronic acid and other supporting ingredients to address different dehydration concerns. Whether you need a budget-friendly daily layer, a reparative option for sensitive skin, or a premium formula with extended hydration claims, these products offer concrete solutions for building or boosting your moisture routine.

Our 8 Picks

Neutrogena Hydro Boost Hyaluronic Acid Serum for Face & Neck, Lightweight Daily Hydrating Serum with Hyaluronic Acid for Dry Skin, Oil-Free, Non-Comedogenic, Fragrance-Free, 1 fl. oz
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Neutrogena

Neutrogena Hydro Boost Hyaluronic Acid Serum for Face & Neck, Lightweight Daily Hydrating Serum with Hyaluronic Acid for Dry Skin, Oil-Free, Non-Comedogenic, Fragrance-Free, 1 fl. oz

glycerin serum drugstore fragrance-free hydrating serum

What it is

A lightweight daily hydrating face and neck serum formulated with hyaluronic acid and glycerin to attract and retain moisture.

Why it's worth it

The serum penetrates deeply to restore moisture in dry, tired skin, leaving it soft and supple. Brand states the formula combines purified hyaluronic acid, trehalose, and glycerin for long-lasting hydration without a sticky feel. Its oil-free, fragrance-free texture makes it suitable for layering under moisturizer or using alone. Well suited to those with chronically dry skin who want a no-fuss hydrating step that absorbs quickly.

Caveat

The lightweight consistency may not provide enough emollience for extremely flaky or compromised barriers without an occlusive moisturizer on top.

The INKEY List Hyaluronic Acid Serum - Delivers Instant and Lasting Deep Hydration, Plumps Dry Skin, Vegan & Suitable For All Skin Types
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The INKEY List

The INKEY List Hyaluronic Acid Serum - Delivers Instant and Lasting Deep Hydration, Plumps Dry Skin, Vegan & Suitable For All Skin Types

hyaluronic acid serum budget vegan hydrating serum

What it is

A straightforward hyaluronic acid serum that provides instant and lasting hydration to plump dry skin.

Why it's worth it

The formula uses multiple molecular weights of hyaluronic acid to hydrate at different levels of the skin, helping to reduce the look of fine dry lines. The brand states it works as a daily essential that helps other skincare products perform better by providing a hydrated base. Its simple, vegan formula suits those new to glycerin-based hydration and layering. A good fit for dry skin needing an affordable, no-frills serum that doesn't pill under makeup.

Caveat

The thin watery texture may require quick application and a moisturizer immediately after to prevent moisture loss in very dry environments.

La Roche-Posay Hyalu B5 Pure Hyaluronic Acid Serum for Face, Vitamin B5 + Hyaluronic Acid + Madecassoside, Hydrating Serum Visibly Plumps Skin, Sensitive Skin Safe, Anti Aging, Oil-Free
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La Roche-Posay

La Roche-Posay Hyalu B5 Pure Hyaluronic Acid Serum for Face, Vitamin B5 + Hyaluronic Acid + Madecassoside, Hydrating Serum Visibly Plumps Skin, Sensitive Skin Safe, Anti Aging, Oil-Free

barrier repair serum anti-aging hydrating serum

What it is

A concentrated anti-aging hydrating serum with pure hyaluronic acid, vitamin B5, and madecassoside to plump and repair the skin barrier.

Why it's worth it

Brand states this serum combines glycerin, hyaluronic acid, and madecassoside to deliver rich hydration that visibly plumps skin and reduces fine lines. It is formulated to restore the moisture barrier, making it particularly suitable for sensitive skin experiencing dehydration. The oil-free formula absorbs without heaviness, providing a cushiony feel that preps skin for makeup. Well suited to those wanting a reparative, plumping serum that can calm tight, reactive dry skin.

Caveat

The texture can feel slightly tacky if over-applied, so start with a few drops and press into damp skin.

Vichy Mineral 89 Booster, Pure Hyaluronic Acid Serum for Face with Polyglutamic Acid for Skin Barrier Repair, Plumps & Hydrates, Lightweight Hydrating Serum, Oil-Free, Non-Sticky
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Vichy

Vichy Mineral 89 Booster, Pure Hyaluronic Acid Serum for Face with Polyglutamic Acid for Skin Barrier Repair, Plumps & Hydrates, Lightweight Hydrating Serum, Oil-Free, Non-Sticky

hyaluronic acid booster mineral water serum

What it is

A mineral-rich hydrating booster serum with hyaluronic acid and polyglutamic acid designed to strengthen the skin barrier and provide lasting moisture.

Why it's worth it

The brand indicates that this serum uses a blend of hyaluronic acid and polyglutamic acid to instantly boost hydration and help lock it in, with 89% Vichy Volcanic Water rich in minerals to support the skin's barrier. Its lightweight, non-sticky gel texture quickly absorbs, making it ideal for layering under richer moisturizers. Brand states clinical testing showed a visible improvement in hydration and plumpness. A good fit for those seeking a fragrance-free, minimalist hydrator that won't interfere with other actives.

Caveat

It may not provide sufficient standalone moisture for very dry skin in low-humidity conditions without a cream on top.

Clinique Moisture Surge 100H Auto-Replenishing Hydrator Oil Free Face Moisturizer | With Hyaluronic Acid, Aloe Bioferment and Vitamins C + E | For All Skin Types | Hydrating + Moisturizing
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Clinique

Clinique Moisture Surge 100H Auto-Replenishing Hydrator Oil Free Face Moisturizer | With Hyaluronic Acid, Aloe Bioferment and Vitamins C + E | For All Skin Types | Hydrating + Moisturizing

gel-cream hydrator oil-free moisturizer for dry skin

What it is

An oil-free gel-cream hydrator that uses hyaluronic acid and aloe bioferment to provide long-lasting moisture that auto-replenishes after cleansing.

Why it's worth it

The gel-cream texture sinks in rapidly, delivering a burst of hydration that the brand says continues for up to 100 hours even after washing the face. It's formulated with glycerin and hyaluronic acid to draw in water, while aloe bioferment helps soothe dry, tight skin. Despite being a moisturizer, its lightweight, serum-like consistency layers well over other treatments. Well suited to individuals with dry yet pore-clog-prone skin who want intense hydration without oil or heaviness.

Caveat

While marketed as a moisturizer, it may not be occlusive enough to seal in hydration for those with severely dry skin in winter; a separate cream might be needed.

Peter Thomas Roth Water Drench® Hyaluronic Glow Serum
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Peter Thomas Roth

Peter Thomas Roth Water Drench® Hyaluronic Glow Serum

hyaluronic glow serum dewy skin serum

What it is

A hyaluronic acid-rich serum that drenches skin with moisture to create a dewy, luminous appearance.

Why it's worth it

The formula contains a 75% Hyaluronic Acid Complex to plump dry skin with intense hydration, plus 3% HydraFence for sustained moisture retention—brand states it provides up to 120 hours of enhanced hydration. A 5% Ceramide Complex works to improve the look of fine lines, while mineral-rich malachite helps detoxify skin's appearance. Its lightweight, water-gel texture disappears quickly, leaving a soft glow without stickiness. A good fit for those wanting a premium, glow-enhancing serum that delivers both immediate plumping and long-term barrier support.

Caveat

The high hyaluronic acid content might cause a slight tingling on very sensitive or compromised skin, so patch testing is advised.

Hyaluronic Serum 1 Fl Oz, Anti Aging Serum, Plumps Fine Lines and Wrinkles, Boosts Firmness, Award-Winning Luxury Skincare By Dr. Barbara Sturm
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Dr. Barbara Sturm

Hyaluronic Serum 1 Fl Oz, Anti Aging Serum, Plumps Fine Lines and Wrinkles, Boosts Firmness, Award-Winning Luxury Skincare By Dr. Barbara Sturm

luxury hyaluronic serum anti-aging plumping serum

What it is

A luxury anti-aging hydrating serum that uses hyaluronic acid to plump fine lines and boost firmness.

Why it's worth it

This serum is formulated to deliver intense hydration through a blend of hyaluronic acid in different weights, attracting moisture deep into the skin to smooth the look of wrinkles. The brand states it instantly boosts firmness and leaves a visibly plumper complexion. Its lightweight, water-light texture absorbs in seconds, making it suitable for layering with richer treatments. Well suited to those who prioritize a sensory, fast-absorbing formula and are willing to invest in a high-end daily hydrating step.

Caveat

At a premium price point, it may be less accessible for daily use, and the formula might not contain additional barrier-supporting lipids for extremely parched skin.

Paula's Choice BOOST Hyaluronic Acid Booster Face Serum with Ceramides, Plumps Fine Lines and Wrinkles, Hydrating Hyaluronic Acid Gel for Dry Skin, Fragrance-Free, 0.5 Fl Oz
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Paula's Choice

Paula's Choice BOOST Hyaluronic Acid Booster Face Serum with Ceramides, Plumps Fine Lines and Wrinkles, Hydrating Hyaluronic Acid Gel for Dry Skin, Fragrance-Free, 0.5 Fl Oz

hyaluronic acid booster fragrance-free plumping serum

What it is

A concentrated hyaluronic acid booster serum with ceramides and panthenol that can be used alone or mixed with a moisturizer to amplify hydration.

Why it's worth it

The brand describes it as a specialized matrix of hyaluronic acid, ceramides, and panthenol that penetrates quickly to lock in moisture and visibly plump skin, smoothing fine lines. Its versatile format allows you to customize your hydration level—apply a few drops directly or mix into your favorite moisturizer. The lightweight gel texture is fragrance-free, suiting even reactive skin types. A good fit for someone who wants to intensify the hydrating power of their existing routine without adding another heavy layer.

Caveat

The small 0.5 oz bottle may run out quickly with twice-daily use, especially if mixed into moisturizer.

How to choose

How to choose the right hydrating serums with glycerin and hyaluronic acid for dry skin

Consider your skin's moisture deficit. If your skin is mildly dry and you want a quick-absorbing layer under moisturizer, The INKEY List's thin watery texture or Vichy's lightweight gel may suit you. For chronically dry or reactive skin, La Roche-Posay's madecassoside and vitamin B5 combination or Paula's Choice ceramide-booster format offer reparative elements beyond basic hydration. Evaluate your existing routine. If you already use a rich moisturizer and want to intensify it without adding weight, Paula's Choice booster is designed to mix into other products. If you prefer to streamline steps, Clinique's 100H gel-cream functions as a hydrator-moisturizer hybrid with extended wear claims. Factor in environment and season. Lightweight serums like Neutrogena's or Vichy's may need an occlusive cream on top in winter or low-humidity climates. Peter Thomas Roth's 120-hour hydration claim or Clinique's 100-hour claim may provide more staying power for those in drying environments. Assess sensitivity and texture preferences. Fragrance-free options from Neutrogena, Vichy, and Paula's Choice minimize irritation risk. If tackiness bothers you, note that La Roche-Posay can feel slightly sticky if over-applied, while Peter Thomas Roth's water-gel is specifically described as non-sticky. Calculate long-term value. The INKEY List at $10 and Neutrogena at $19.97 offer accessible entry points for daily use. However, Paula's Choice 0.5 oz size may require frequent repurchasing.

Takeaway

The right hydrating serum depends on how your skin loses moisture, what else you apply, and your budget for daily replenishment. Each of these seven glycerin-based options and one gel-cream hydrator addresses a specific hydration gap—match the formula's supporting ingredients and texture to your routine, and you'll build more resilient, comfortable skin over time.

Frequently Asked Questions

Can I use these serums if I have oily or acne-prone skin?

Several options are explicitly oil-free and non-comedogenic. Neutrogena's formula is oil-free and fragrance-free, while Clinique's gel-cream is marketed as oil-free for all skin types, including those prone to clogged pores. The lightweight, water-gel textures of Vichy and Peter Thomas Roth absorb without residue, making them suitable for oily skin that still needs hydration.

How do I layer these serums with other skincare products?

Apply glycerin-based serums to damp skin after cleansing and before heavier treatments or moisturizers. The INKEY List and Neutrogena absorb quickly and work well under sunscreen and makeup. Paula's Choice booster can be mixed directly into your moisturizer if you want to simplify your routine or add hydration to a thicker cream.

Is the price difference between drugstore and luxury options justified?

The core hydrating ingredients—glycerin and hyaluronic acid—are present across price points. Peter Thomas Roth commands a higher price for additional ingredients like a 75% Hyaluronic Acid Complex, 3% HydraFence, and 5% Ceramide Complex with extended hydration claims. For basic daily hydration, The INKEY List at $10 and Neutrogena at $19.97 deliver comparable moisture-attracting benefits.

Which product works for extremely dry or compromised skin barriers?

La Roche-Posay's Hyalu B5 includes madecassoside and vitamin B5 specifically for barrier repair, while Paula's Choice adds ceramides and panthenol for lipid support. However, even these may need an occlusive moisturizer on top for severely flaky skin, as noted in the caveats for Neutrogena and Vichy as well.

What size should I buy to test a product first?

Paula's Choice comes in a 0.5 oz format that may run out quickly with regular use, making it a costly trial option despite its booster versatility. The INKEY List and Neutrogena offer standard 1 oz sizes at lower price points, providing more time to assess how your skin responds before committing to a larger or more expensive purchase.

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